Integrated Batch and Continuous Flow Process for the Synthesis of Goniothalamin

[Image: see text] An integrated batch and continuous flow process has been developed for the gram-scale synthesis of goniothalamin. The synthetic route hinges upon a telescoped continuous flow Grignard addition followed by an acylation reaction capable of delivering a racemic goniothalamin precursor...

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Publicado en:ACS Omega
Main Authors: Pastre, Julio C., Murray, Philip R. D., Browne, Duncan L., Brancaglion, Guilherme A., Galaverna, Renan S., Pilli, Ronaldo A., Ley, Steven V.
Formato: Artigo
Idioma:Inglês
Publicado: American Chemical Society 2020
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7391960/
https://ncbi.nlm.nih.gov/pubmed/32743225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.0c02390
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