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Synthesis and Utilization of Nitroalkyne Equivalents in Batch and Continuous Flow

We report a method for overcoming the low stability of nitroalkynes through the development of nitrated vinyl silyltriflate equivalents. Because of their instability, nitroalkynes have only rarely been utilized in synthesis. The reactivity of these silyltriflates, which are prepared in situ, is exem...

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Pubblicato in:Angew Chem Int Ed Engl
Autori principali: Morse, Peter D., Jamison, Timothy F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5698803/
https://ncbi.nlm.nih.gov/pubmed/28929565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201706157
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