Resveratrol protects against apoptosis induced by interleukin-1β in nucleus pulposus cells via activating mTOR/caspase-3 and GSK-3β/caspase-3 pathways

Objective: The purpose of the present study was to investigate the specific downstream signaling pathway mediated by PI3K/Akt in resveratrol (RES) anti-apoptosis of nucleus pulposus cells (NPCs). Materials and methods: Human NPCs were cultured and divided into six groups. Interleukin (IL)-1β was use...

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Vydáno v:Biosci Rep
Hlavní autoři: Guo, Xiaohui, Bai, Xiaoliang, Zhang, Feng, Zheng, Long, Ding, Wenyuan, Yang, Sidong
Médium: Artigo
Jazyk:Inglês
Vydáno: Portland Press Ltd. 2020
Témata:
Aging
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7391128/
https://ncbi.nlm.nih.gov/pubmed/32696949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20202019
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