VISTA is a checkpoint regulator for naïve T cell quiescence and peripheral tolerance

Negative checkpoint regulators (NCRs) temper the T cell immune response to self-antigens and limit the development of autoimmunity. Unlike all other NCRs that are expressed on activated T lymphocytes, V-type immunoglobulin domain-containing suppressor of T-cell activation (VISTA) is expressed on naï...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Science
Egile Nagusiak: ElTanbouly, Mohamed A., Zhao, Yanding, Nowak, Elizabeth, Li, Jiannan, Schaafsma, Evelien, Le Mercier, Isabelle, Ceeraz, Sabrina, Lines, J. Louise, Peng, Changwei, Carriere, Catherine, Huang, Xin, Day, Maria, Koehn, Brent, Lee, Sam W., Morales, Milagros Silva, Hogquist, Kristin A., Jameson, Stephen C., Mueller, Daniel, Rothstein, Jay, Blazar, Bruce R., Cheng, Chao, Noelle, Randolph J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2020
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7391053/
https://ncbi.nlm.nih.gov/pubmed/31949051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aay0524
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