VISTA Re-programs Macrophage Biology Through the Combined Regulation of Tolerance and Anti-inflammatory Pathways

We present the novel finding that V-domain Ig suppressor of T cell activation (VISTA) negatively regulates innate inflammation through the transcriptional and epigenetic re-programming of macrophages. Representative of VISTA re-programming is the ability of VISTA agonistic antibodies to augment LPS...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: ElTanbouly, Mohamed A., Schaafsma, Evelien, Smits, Nicole C., Shah, Parth, Cheng, Chao, Burns, Christopher, Blazar, Bruce R., Noelle, Randolph J., Mabaera, Rodwell
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7593571/
https://ncbi.nlm.nih.gov/pubmed/33178206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.580187
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados