VISTA Re-programs Macrophage Biology Through the Combined Regulation of Tolerance and Anti-inflammatory Pathways

We present the novel finding that V-domain Ig suppressor of T cell activation (VISTA) negatively regulates innate inflammation through the transcriptional and epigenetic re-programming of macrophages. Representative of VISTA re-programming is the ability of VISTA agonistic antibodies to augment LPS...

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Dades bibliogràfiques
Publicat a:Front Immunol
Autors principals: ElTanbouly, Mohamed A., Schaafsma, Evelien, Smits, Nicole C., Shah, Parth, Cheng, Chao, Burns, Christopher, Blazar, Bruce R., Noelle, Randolph J., Mabaera, Rodwell
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2020
Matèries:
Immunology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7593571/
https://ncbi.nlm.nih.gov/pubmed/33178206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.580187
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