H3K9me3 maintenance on a human artificial chromosome is required for segregation but not centromere epigenetic memory

Most eukaryotic centromeres are located within heterochromatic regions. Paradoxically, heterochromatin can also antagonize de novo centromere formation, and some centromeres lack it altogether. In order to investigate the importance of heterochromatin at centromeres, we used epigenetic engineering o...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Cell Sci
Prif Awduron: Martins, Nuno M. C., Cisneros-Soberanis, Fernanda, Pesenti, Elisa, Kochanova, Natalia Y., Shang, Wei-Hao, Hori, Tetsuya, Nagase, Takahiro, Kimura, Hiroshi, Larionov, Vladimir, Masumoto, Hiroshi, Fukagawa, Tatsuo, Earnshaw, William C.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Company of Biologists Ltd 2020
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7390644/
https://ncbi.nlm.nih.gov/pubmed/32576667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.242610
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