H3K9me3 maintenance on a human artificial chromosome is required for segregation but not centromere epigenetic memory

Most eukaryotic centromeres are located within heterochromatic regions. Paradoxically, heterochromatin can also antagonize de novo centromere formation, and some centromeres lack it altogether. In order to investigate the importance of heterochromatin at centromeres, we used epigenetic engineering o...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:J Cell Sci
Huvudupphovsmän: Martins, Nuno M. C., Cisneros-Soberanis, Fernanda, Pesenti, Elisa, Kochanova, Natalia Y., Shang, Wei-Hao, Hori, Tetsuya, Nagase, Takahiro, Kimura, Hiroshi, Larionov, Vladimir, Masumoto, Hiroshi, Fukagawa, Tatsuo, Earnshaw, William C.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Company of Biologists Ltd 2020
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7390644/
https://ncbi.nlm.nih.gov/pubmed/32576667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.242610
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk