H3K9me3 maintenance on a human artificial chromosome is required for segregation but not centromere epigenetic memory

Most eukaryotic centromeres are located within heterochromatic regions. Paradoxically, heterochromatin can also antagonize de novo centromere formation, and some centromeres lack it altogether. In order to investigate the importance of heterochromatin at centromeres, we used epigenetic engineering o...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:J Cell Sci
Autores principales: Martins, Nuno M. C., Cisneros-Soberanis, Fernanda, Pesenti, Elisa, Kochanova, Natalia Y., Shang, Wei-Hao, Hori, Tetsuya, Nagase, Takahiro, Kimura, Hiroshi, Larionov, Vladimir, Masumoto, Hiroshi, Fukagawa, Tatsuo, Earnshaw, William C.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Company of Biologists Ltd 2020
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7390644/
https://ncbi.nlm.nih.gov/pubmed/32576667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.242610
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares