DICER1 in the Pathogenesis of Age-related Macular Degeneration (AMD) - Alu RNA Accumulation versus miRNA Dysregulation

DICER1 deficiency in the retinal pigment epithelium (RPE) was associated with the accumulation of Alu transcripts and implicated in geographic atrophy (GA), a form of age-related macular degeneration (AMD), an eye disease leading to blindness in millions of people. Although the exact mechanism of th...

Full description

Saved in:
Bibliographic Details
Published in:Aging Dis
Main Authors: Kaarniranta, Kai, Pawlowska, Elzbieta, Szczepanska, Joanna, Blasiak, Janusz
Format: Artigo
Language:Inglês
Published: JKL International LLC 2020
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7390522/
https://ncbi.nlm.nih.gov/pubmed/32765950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14336/AD.2019.0809
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items