Interplay between Autophagy and the Ubiquitin-Proteasome System and Its Role in the Pathogenesis of Age-Related Macular Degeneration

Age-related macular degeneration (AMD) is a complex eye disease with many pathogenesis factors, including defective cellular waste management in retinal pigment epithelium (RPE). Main cellular waste in AMD are: all-trans retinal, drusen and lipofuscin, containing unfolded, damaged and unneeded prote...

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Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Blasiak, Janusz, Pawlowska, Elzbieta, Szczepanska, Joanna, Kaarniranta, Kai
Format: Artigo
Language:Inglês
Published: MDPI 2019
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6337628/
https://ncbi.nlm.nih.gov/pubmed/30626110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20010210
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