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DICER1 in the Pathogenesis of Age-related Macular Degeneration (AMD) - Alu RNA Accumulation versus miRNA Dysregulation

DICER1 deficiency in the retinal pigment epithelium (RPE) was associated with the accumulation of Alu transcripts and implicated in geographic atrophy (GA), a form of age-related macular degeneration (AMD), an eye disease leading to blindness in millions of people. Although the exact mechanism of th...

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Detalhes bibliográficos
Publicado no:Aging Dis
Main Authors: Kaarniranta, Kai, Pawlowska, Elzbieta, Szczepanska, Joanna, Blasiak, Janusz
Formato: Artigo
Idioma:Inglês
Publicado em: JKL International LLC 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7390522/
https://ncbi.nlm.nih.gov/pubmed/32765950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14336/AD.2019.0809
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