Intermittent parathyroid hormone (1–34) supplementation of bone marrow stromal cell cultures may inhibit hypertrophy, but at the expense of chondrogenesis

BACKGROUND: Bone marrow stromal cells (BMSC) have promise in cartilage tissue engineering, but for their potential to be fully realised, the propensity to undergo hypertrophy must be mitigated. The literature contains diverging reports on the effect of parathyroid hormone (PTH) on BMSC differentiati...

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Bibliographic Details
Published in:Stem Cell Res Ther
Main Authors: Music, Ena, Futrega, Kathryn, Palmer, James S., Kinney, Mackenzie, Lott, Bill, Klein, Travis J., Doran, Michael R.
Format: Artigo
Language:Inglês
Published: BioMed Central 2020
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7389809/
https://ncbi.nlm.nih.gov/pubmed/32727579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-020-01820-6
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