Intermittent parathyroid hormone (1–34) supplementation of bone marrow stromal cell cultures may inhibit hypertrophy, but at the expense of chondrogenesis

BACKGROUND: Bone marrow stromal cells (BMSC) have promise in cartilage tissue engineering, but for their potential to be fully realised, the propensity to undergo hypertrophy must be mitigated. The literature contains diverging reports on the effect of parathyroid hormone (PTH) on BMSC differentiati...

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Enregistré dans:
Détails bibliographiques
Publié dans:Stem Cell Res Ther
Auteurs principaux: Music, Ena, Futrega, Kathryn, Palmer, James S., Kinney, Mackenzie, Lott, Bill, Klein, Travis J., Doran, Michael R.
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2020
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7389809/
https://ncbi.nlm.nih.gov/pubmed/32727579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-020-01820-6
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