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Direct bone marrow HSC transplantation enhances local engraftment at the expense of systemic engraftment in NSG mice

Direct bone marrow (BM) injection has been proposed as a strategy to bypass homing inefficiencies associated with intravenous (IV) hematopoietic stem cell (HSC) transplantation. Despite physical delivery into the BM cavity, many donor cells are rapidly redistributed by vascular perfusion, perhaps co...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Futrega, Kathryn, Lott, William B., Doran, Michael R.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4827391/
https://ncbi.nlm.nih.gov/pubmed/27065210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep23886
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