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Targeting the PI3K/Akt/mTOR pathway in estrogen-receptor positive HER2 negative advanced breast cancer

Recently many therapeutic classes have emerged in advanced hormone receptor-positive breast cancer, which is the leading cause of cancer death in women. In absence of visceral crisis, treatment relies on endocrine therapy combined with cyclin dependent kinase 4 and 6 inhibitor. Many mechanisms lead...

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Bibliografiske detaljer
Udgivet i:Ther Adv Med Oncol
Main Authors: du Rusquec, Pauline, Blonz, Cyriac, Frenel, Jean Sebastien, Campone, Mario
Format: Artigo
Sprog:Inglês
Udgivet: SAGE Publications 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7388095/
https://ncbi.nlm.nih.gov/pubmed/32782489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1758835920940939
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