Accelerated cryo-EM-guided determination of three-dimensional RNA-only structures

The discovery and design of biologically important RNA molecules is outpacing three-dimensional structural characterization. Here, we demonstrate that cryo-EM can routinely resolve maps of RNA-only systems and that these maps enable sub-nanometer resolution coordinate estimation when complemented wi...

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Publicat a:Nat Methods
Autors principals: Kappel, Kalli, Zhang, Kaiming, Su, Zhaoming, Watkins, Andrew M., Kladwang, Wipapat, Li, Shanshan, Pintilie, Grigore, Topkar, Ved V., Rangan, Ramya, Zheludev, Ivan N., Yesselman, Joseph D., Chiu, Wah, Das, Rhiju
Format: Artigo
Idioma:Inglês
Publicat: 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7386730/
https://ncbi.nlm.nih.gov/pubmed/32616928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41592-020-0878-9
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