Llwytho...

Inhibitors of VPS34 and lipid metabolism suppress SARS-CoV-2 replication

Therapeutics targeting replication of SARS coronavirus 2 (SARS-CoV-2) are urgently needed. Coronaviruses rely on host membranes for entry, establishment of replication centers and egress. Compounds targeting cellular membrane biology and lipid biosynthetic pathways have previously shown promise as a...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:bioRxiv
Prif Awduron: Silvas, Jesus A., Jureka, Alexander S., Nicolini, Anthony M., Chvatal, Stacie A., Basler, Christopher F.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Cold Spring Harbor Laboratory 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7386504/
https://ncbi.nlm.nih.gov/pubmed/32743584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.07.18.210211
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