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Inhibitors of VPS34 and lipid metabolism suppress SARS-CoV-2 replication

Therapeutics targeting replication of SARS coronavirus 2 (SARS-CoV-2) are urgently needed. Coronaviruses rely on host membranes for entry, establishment of replication centers and egress. Compounds targeting cellular membrane biology and lipid biosynthetic pathways have previously shown promise as a...

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Detaylı Bibliyografya
Yayımlandı:bioRxiv
Asıl Yazarlar: Silvas, Jesus A., Jureka, Alexander S., Nicolini, Anthony M., Chvatal, Stacie A., Basler, Christopher F.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Cold Spring Harbor Laboratory 2020
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7386504/
https://ncbi.nlm.nih.gov/pubmed/32743584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.07.18.210211
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