Inhibitors of VPS34 and fatty-acid metabolism suppress SARS-CoV-2 replication

Coronaviruses rely on host membranes for entry, establishment of replication centers, and egress. Compounds targeting cellular membrane biology and lipid biosynthetic pathways have previously shown promise as antivirals and are actively being pursued as treatments for other conditions. Here, we test...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Rep
Prif Awduron: Williams, Caroline G., Jureka, Alexander S., Silvas, Jesus A., Nicolini, Anthony M., Chvatal, Stacie A., Carlson-Stevermer, Jared, Oki, Jennifer, Holden, Kevin, Basler, Christopher F.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Authors. 2021
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8289695/
https://ncbi.nlm.nih.gov/pubmed/34320401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2021.109479
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