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Inhibitors of VPS34 and lipid metabolism suppress SARS-CoV-2 replication

Therapeutics targeting replication of SARS coronavirus 2 (SARS-CoV-2) are urgently needed. Coronaviruses rely on host membranes for entry, establishment of replication centers and egress. Compounds targeting cellular membrane biology and lipid biosynthetic pathways have previously shown promise as a...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:bioRxiv
Päätekijät: Silvas, Jesus A., Jureka, Alexander S., Nicolini, Anthony M., Chvatal, Stacie A., Basler, Christopher F.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Cold Spring Harbor Laboratory 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7386504/
https://ncbi.nlm.nih.gov/pubmed/32743584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.07.18.210211
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