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Inhibitors of VPS34 and lipid metabolism suppress SARS-CoV-2 replication

Therapeutics targeting replication of SARS coronavirus 2 (SARS-CoV-2) are urgently needed. Coronaviruses rely on host membranes for entry, establishment of replication centers and egress. Compounds targeting cellular membrane biology and lipid biosynthetic pathways have previously shown promise as a...

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Bibliografische gegevens
Gepubliceerd in:bioRxiv
Hoofdauteurs: Silvas, Jesus A., Jureka, Alexander S., Nicolini, Anthony M., Chvatal, Stacie A., Basler, Christopher F.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Cold Spring Harbor Laboratory 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7386504/
https://ncbi.nlm.nih.gov/pubmed/32743584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.07.18.210211
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