Progenitor identification and SARS-CoV-2 infection in long-term human distal lung organoid cultures

The distal lung contains terminal bronchioles and alveoli that facilitate gas exchange and is affected by disorders including interstitial lung disease, cancer, and SARS-CoV-2-associated COVID-19 pneumonia. Investigations of these localized pathologies have been hindered by a lack of 3D in vitro hum...

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Publicado no:bioRxiv
Main Authors: Salahudeen, Ameen A., Choi, Shannon S., Rustagi, Arjun, Zhu, Junjie, de la O, Sean M., Flynn, Ryan A, Margalef-Català, Mar, Santos, António J.M., Ju, Jihang, Batish, Arpit, van Unen, Vincent, Usui, Tatsuya, Zheng, Grace X.Y., Edwards, Caitlin E., Wagar, Lisa E, Luca, Vincent, Anchang, Benedict, Nagendran, Monica, Nguyen, Khanh, Hart, Daniel J., Terry, Jessica M., Belgrader, Phillip, Ziraldo, Solongo B., Mikkelsen, Tarjei S., Harbury, Pehr B., Glenn, Jeffrey S., Garcia, K. Christopher, Davis, Mark M., Baric, Ralph S., Sabatti, Chiara, Amieva, Manuel R., Blish, Catherine A., Desai, Tushar J., Kuo, Calvin J.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7386503/
https://ncbi.nlm.nih.gov/pubmed/32743583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.07.27.212076
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