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HIV-1 Integrase and Virus and Cell DNAs: Complex Formation and Perturbation by Inhibitors of Integration
HIV-1 integrase (IN) catalyzes integration of viral DNA into cell DNA through 30-processing of viral DNA and strand transfer reactions. To learn on binding of IN to DNAs and IN inhibition we applied spectroscopy (circular dichroism, fluorescence) in a simplified model consisting in a peptide analogu...
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| Publicado en: | Neurochem Res |
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| Autores principales: | , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2009
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7386435/ https://ncbi.nlm.nih.gov/pubmed/19937113 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11064-009-0098-2 |
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