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Blockade of the lysophosphatidylserine lipase ABHD12 potentiates ferroptosis in cancer cells
Ferroptosis is a type of cell death caused by the pathogenic accumulation of lipid hydroperoxides. Pharmacological mechanisms to induce ferroptosis may provide a way to kill cancer cells that are resistant to other forms of cell death like apoptosis. Nonetheless, the proteins that regulate ferroptot...
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| Published in: | ACS Chem Biol |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2020
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7386317/ https://ncbi.nlm.nih.gov/pubmed/32195565 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.0c00086 |
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