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Mapping the neuroanatomy of ABHD16A–ABHD12 & lysophosphatidylserines provides new insights into the pathophysiology of the human neurological disorder PHARC

Lysophosphatidylserine (lyso-PS), a lysophospholipid derived from phosphatidylserine (PS), has emerged as a potent signaling lipid in mammalian physiology. In vivo, the metabolic serine hydrolases ABHD16A and ABHD12 are major lipases that biosynthesize and degrade lyso-PS respectively. Of biomedical...

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Detalhes bibliográficos
Publicado no:Biochemistry
Main Authors: Singh, Shubham, Joshi, Alaumy, Kamat, Siddhesh S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7311203/
https://ncbi.nlm.nih.gov/pubmed/32462874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.0c00349
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