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Exploring the energy landscape of a molecular engineered analog of a tumor-homing peptide
Recently a new non-coded amino acid was designed as a replacement for Arg, to protect the tumor-homing pentapeptide CREKA (Cys-Arg-Glu-Lys-Ala) from proteases. This constrained Arg analog, denoted c(5)Arg, was engineered to also promote the stability of the CREKA bioactive conformation. The conforma...
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| Publicat a: | Phys Chem Chem Phys |
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| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7385989/ https://ncbi.nlm.nih.gov/pubmed/21258721 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c0cp02572k |
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