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Spatiotemporal regulation of ΔNp63 by TGFβ-regulated miRNAs is essential for cancer metastasis

ΔNp63 is a transcription factor of the p53 family and has crucial functions in normal development and disease. The expression pattern of ΔNp63 in human cancer suggests dynamic regulation of this isoform during cancer progression and metastasis. Many primary and metastatic tumors express high levels...

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Détails bibliographiques
Publié dans:Cancer Res
Auteurs principaux: Bui, Ngoc H. B., Napoli, Marco, Davis, Andrew J., Abbas, Hussein A., Rajapakshe, Kimal, Coarfa, Cristian, Flores, Elsa R.
Format: Artigo
Langue:Inglês
Publié: 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7385751/
https://ncbi.nlm.nih.gov/pubmed/32312834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-19-2733
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