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Targeting Rad51 as a strategy for the treatment of melanoma cells resistant to MAPK pathway inhibition
Rad51 is an essential factor of the homologous recombination DNA repair pathway and therefore plays an important role in maintaining genomic stability. We show that RAD51 and other homologous recombination repair genes are overexpressed in metastatic melanoma cell lines and in melanoma patient sampl...
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| Publicado no: | Cell Death Dis |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7385107/ https://ncbi.nlm.nih.gov/pubmed/32719412 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-2702-y |
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