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β-Catenin Signaling Increases during Melanoma Progression and Promotes Tumor Cell Survival and Chemoresistance

Beta-catenin plays an important role in embryogenesis and carcinogenesis by controlling either cadherin-mediated cell adhesion or transcriptional activation of target gene expression. In many types of cancers nuclear translocation of beta-catenin has been observed. Our data indicate that during mela...

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Detalhes bibliográficos
Main Authors: Sinnberg, Tobias, Menzel, Moritz, Ewerth, Daniel, Sauer, Birgit, Schwarz, Michael, Schaller, Martin, Garbe, Claus, Schittek, Birgit
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3157382/
https://ncbi.nlm.nih.gov/pubmed/21858114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023429
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