Repurposing Leflunomide for Relapsed/Refractory Multiple Myeloma: A Phase 1 Study

The inexpensive, well-tolerated, immunomodulatory agent leflunomide, used extensively for the treatment of rheumatoid arthritis, has been shown to produce significant activity against multiple myeloma (MM) in pre-clinical studies. We conducted a phase 1 study (clinicaltrials.gov: NCT02509052) of sin...

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Bibliographic Details
Published in:Leuk Lymphoma
Main Authors: Rosenzweig, Michael, Palmer, Joycelynne, Tsai, Ni-Chun, Synold, Tim, Wu, Xiwei, Tao, Shu, Hammond, Samantha N, Buettner, Ralf, Duarte, Lupe, Htut, Myo, Karanes, Chatchada, Nathwani, Nitya, Pichiorri, Flavia, Sahebi, Firoozeh, Sanchez, James F, Chowdhury, Arnab, Krishnan, Amrita, Forman, Stephen J, Rosen, Steven T
Format: Artigo
Language:Inglês
Published: 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7384948/
https://ncbi.nlm.nih.gov/pubmed/32268821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10428194.2020.1742900
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