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Inducing Apoptosis through Upregulation of p53: Structure-Activity Exploration of Anthraquinone Analogs

We previously reported a series of p53-elevating anthraquinone compounds with considerable cytotoxicity for acute lymphatic leukemia (ALL) cells. To further develop this class of compounds, we examined the effect of a few key structural features on the anticancer structure-activity relationship in A...

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Detalhes bibliográficos
Publicado no:Med Chem Res
Main Authors: Anifowose, Abiodun, Agbowuro, Ayodeji A., Tripathi, Ravi, Lu, Wen, Tan, Chalet, Yang, Xiaoxiao, Wang, Binghe
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7384666/
https://ncbi.nlm.nih.gov/pubmed/32719577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00044-020-02563-y
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