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Elimination of dormant, autophagic ovarian cancer cells and xenografts through enhanced sensitivity to ALK inhibition

PURPOSE: Poor outcomes for ovarian cancer patients relate to dormant, drug resistant cancer cells that survive following primary surgery and chemotherapy. Ovarian cancer (OvCa) cells persist in poorly vascularized scars on the peritoneal surface and depend upon autophagy to survive nutrient deprivat...

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Библиографические подробности
Опубликовано в: :	Cancer
Главные авторы:	Blessing, Alicia M., Santiago-O’Farrill, Janice M., Mao, Weiqun, Pang, Lan, Ning, Jing, Pak, Daewoo, Bollu, Lakshmi Reddy, Rask, Philip, Iles, LaKesla, Tran, Samantha, Elmir, Ezzeddine, Bartholomeusz, Geoffrey, Langley, Robert, Lu, Zhen, Bast, Robert C.
Формат:	Artigo
Язык:	Inglês
Опубликовано:	2020
Предметы:	Article
Online-ссылка:	https://ncbi.nlm.nih.gov/pmc/articles/PMC7384209/ https://ncbi.nlm.nih.gov/pubmed/32484926 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.32985
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Elimination of dormant, autophagic ovarian cancer cells and xenografts through enhanced sensitivity to ALK inhibition

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