Elimination of dormant, autophagic ovarian cancer cells and xenografts through enhanced sensitivity to ALK inhibition

PURPOSE: Poor outcomes for ovarian cancer patients relate to dormant, drug resistant cancer cells that survive following primary surgery and chemotherapy. Ovarian cancer (OvCa) cells persist in poorly vascularized scars on the peritoneal surface and depend upon autophagy to survive nutrient deprivat...

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Publicado en:Cancer
Main Authors: Blessing, Alicia M., Santiago-O’Farrill, Janice M., Mao, Weiqun, Pang, Lan, Ning, Jing, Pak, Daewoo, Bollu, Lakshmi Reddy, Rask, Philip, Iles, LaKesla, Tran, Samantha, Elmir, Ezzeddine, Bartholomeusz, Geoffrey, Langley, Robert, Lu, Zhen, Bast, Robert C.
Formato: Artigo
Idioma:Inglês
Publicado: 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7384209/
https://ncbi.nlm.nih.gov/pubmed/32484926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.32985
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