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Enhancing the sensitivity of the thymidine kinase assay by using DNA repair‐deficient human TK6 cells
The OECD guidelines define the bioassays of identifying mutagenic chemicals, including the thymidine kinase (TK) assay, which specifically detects the mutations that inactivate the TK gene in the human TK6 lymphoid line. However, the sensitivity of this assay is limited because it detects mutations...
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| Publicado no: | Environ Mol Mutagen |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley & Sons, Inc.
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7384079/ https://ncbi.nlm.nih.gov/pubmed/32243652 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/em.22371 |
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