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Adaptive Flexible Sialylated Nanogels as Highly Potent Influenza A Virus Inhibitors

Flexible multivalent 3D nanosystems that can deform and adapt onto the virus surface via specific ligand–receptor multivalent interactions can efficiently block virus adhesion onto the cell. We here report on the synthesis of a 250 nm sized flexible sialylated nanogel that adapts onto the influenza...

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Vydáno v:Angew Chem Int Ed Engl
Hlavní autoři: Bhatia, Sumati, Hilsch, Malte, Cuellar‐Camacho, Jose Luis, Ludwig, Kai, Nie, Chuanxiong, Parshad, Badri, Wallert, Matthias, Block, Stephan, Lauster, Daniel, Böttcher, Christoph, Herrmann, Andreas, Haag, Rainer
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7384064/
https://ncbi.nlm.nih.gov/pubmed/32441859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.202006145
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