Heteromultivalent topology-matched nanostructures as potent and broad-spectrum influenza A virus inhibitors

Here, we report the topology-matched design of heteromultivalent nanostructures as potent and broad-spectrum virus entry inhibitors based on the host cell membrane. Initially, we investigate the virus binding dynamics to validate the better binding performance of the heteromultivalent moieties as co...

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Dades bibliogràfiques
Publicat a:Sci Adv
Autors principals: Nie, Chuanxiong, Stadtmüller, Marlena, Parshad, Badri, Wallert, Matthias, Ahmadi, Vahid, Kerkhoff, Yannic, Bhatia, Sumati, Block, Stephan, Cheng, Chong, Wolff, Thorsten, Haag, Rainer
Format: Artigo
Idioma:Inglês
Publicat: American Association for the Advancement of Science 2021
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7775783/
https://ncbi.nlm.nih.gov/pubmed/33523846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abd3803
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