Neuron-derived exosomes-transmitted miR-124-3p protect traumatically injured spinal cord by suppressing the activation of neurotoxic microglia and astrocytes

BACKGROUND: Spinal cord injury (SCI) is a catastrophic injury that can cause irreversible motor dysfunction with high disability. Exosomes participate in the transport of miRNAs and play an essential role in intercellular communication via transfer of genetic material. However, the miRNAs in exosome...

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Detalles Bibliográficos
Publicado en:J Nanobiotechnology
Main Authors: Jiang, Dongdong, Gong, Fangyi, Ge, Xuhui, Lv, Chengtang, Huang, Chenyu, Feng, Shuang, Zhou, Zheng, Rong, Yuluo, Wang, Jiaxing, Ji, Chengyue, Chen, Jian, Zhao, Wene, Fan, Jin, Liu, Wei, Cai, Weihua
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2020
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7382861/
https://ncbi.nlm.nih.gov/pubmed/32711535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12951-020-00665-8
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