Neuron-derived exosomes-transmitted miR-124-3p protect traumatically injured spinal cord by suppressing the activation of neurotoxic microglia and astrocytes

BACKGROUND: Spinal cord injury (SCI) is a catastrophic injury that can cause irreversible motor dysfunction with high disability. Exosomes participate in the transport of miRNAs and play an essential role in intercellular communication via transfer of genetic material. However, the miRNAs in exosome...

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Dades bibliogràfiques
Publicat a:J Nanobiotechnology
Autors principals: Jiang, Dongdong, Gong, Fangyi, Ge, Xuhui, Lv, Chengtang, Huang, Chenyu, Feng, Shuang, Zhou, Zheng, Rong, Yuluo, Wang, Jiaxing, Ji, Chengyue, Chen, Jian, Zhao, Wene, Fan, Jin, Liu, Wei, Cai, Weihua
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2020
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7382861/
https://ncbi.nlm.nih.gov/pubmed/32711535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12951-020-00665-8
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