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Loratadine Alleviates Advanced Glycation End Product-Induced Activation of NLRP3 Inflammasome in Human Chondrocytes
BACKGROUND: Chondrocytes in joint tissue are responsible for the synthesis and degradation of the cartilage matrix. Chondrocytes have been closely linked to the pathogenesis of osteoarthritis and cartilage damage. Targeted drug intervention directed at chondrocyte function is a promising strategy fo...
Shranjeno v:
izdano v: | Drug Des Devel Ther |
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Main Authors: | , |
Format: | Artigo |
Jezik: | Inglês |
Izdano: |
Dove
2020
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Teme: | |
Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7382759/ https://ncbi.nlm.nih.gov/pubmed/32801633 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S243512 |
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