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A non-invasive far-red light-induced split-Cre recombinase system for controllable genome engineering in mice
The Cre-loxP recombination system is a powerful tool for genetic manipulation. However, there are widely recognized limitations with chemically inducible Cre-loxP systems, and the UV and blue-light induced systems have phototoxicity and minimal capacity for deep tissue penetration. Here, we develop...
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| Publicado en: | Nat Commun |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7381682/ https://ncbi.nlm.nih.gov/pubmed/32709899 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-17530-9 |
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