Kininogen supports inflammation and bacterial spreading during Streptococccus Pyogenes Sepsis

BACKGROUND: High-molecular-weight kininogen is a cofactor of the human contact system, an inflammatory response mechanism that is activated during sepsis. It has been shown that high-molecular-weight kininogen contributes to endotoxemia, but is not critical for local host defense during pneumonia by...

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Detalles Bibliográficos
Publicado en:EBioMedicine
Autores principales: Köhler, Juliane, Maletzki, Claudia, Koczan, Dirk, Frank, Marcus, Springer, Armin, Steffen, Carolin, Revenko, Alexey S., MacLeod, A.Robert, Mikkat, Stefan, Kreikemeyer, Bernd, Oehmcke-Hecht, Sonja
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2020
Materias:
Research paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7381504/
https://ncbi.nlm.nih.gov/pubmed/32707450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2020.102908
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