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The synthetic LPS binding peptide 19-2.5 interferes with clotting and prevents degradation of high molecular weight kininogen in plasma

Sepsis and septic shock are life-threatening conditions and remain an important medical problem, emphasizing the need to identify novel therapeutic approaches. Coagulation dysfunction, hypotension, disturbed microcirculation and multiorgan failure occur frequently. These severe conditions result fro...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Köhler, Juliane, Ehler, Johannes, Kreikemeyer, Bernd, Bajorath, Rika, Schürholz, Tobias, Oehmcke-Hecht, Sonja
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7188841/
https://ncbi.nlm.nih.gov/pubmed/32346013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-64155-5
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