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The synthetic LPS binding peptide 19-2.5 interferes with clotting and prevents degradation of high molecular weight kininogen in plasma

Sepsis and septic shock are life-threatening conditions and remain an important medical problem, emphasizing the need to identify novel therapeutic approaches. Coagulation dysfunction, hypotension, disturbed microcirculation and multiorgan failure occur frequently. These severe conditions result fro...

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Publicat a:Sci Rep
Autors principals: Köhler, Juliane, Ehler, Johannes, Kreikemeyer, Bernd, Bajorath, Rika, Schürholz, Tobias, Oehmcke-Hecht, Sonja
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7188841/
https://ncbi.nlm.nih.gov/pubmed/32346013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-64155-5
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