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The synthetic LPS binding peptide 19-2.5 interferes with clotting and prevents degradation of high molecular weight kininogen in plasma

Sepsis and septic shock are life-threatening conditions and remain an important medical problem, emphasizing the need to identify novel therapeutic approaches. Coagulation dysfunction, hypotension, disturbed microcirculation and multiorgan failure occur frequently. These severe conditions result fro...

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書目詳細資料
發表在:Sci Rep
Main Authors: Köhler, Juliane, Ehler, Johannes, Kreikemeyer, Bernd, Bajorath, Rika, Schürholz, Tobias, Oehmcke-Hecht, Sonja
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7188841/
https://ncbi.nlm.nih.gov/pubmed/32346013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-64155-5
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