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Streptococcus pyogenes Escapes Killing from Extracellular Histones through Plasminogen Binding and Activation by Streptokinase

Histones are small basic proteins and highly conserved among eukaryotes. Their main function is binding, packaging and organizing of DNA in the nucleus, but extracellular histones are also potent antimicrobial proteins. Here we found that Streptococcus pyogenes - an important human pathogen - protec...

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Bibliographische Detailangaben
Veröffentlicht in:J Innate Immun
Hauptverfasser: Nitzsche, Ramona, Köhler, Juliane, Kreikemeyer, Bernd, Oehmcke-Hecht, Sonja
Format: Artigo
Sprache:Inglês
Veröffentlicht: S. Karger AG 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6738899/
https://ncbi.nlm.nih.gov/pubmed/27533300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000448039
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