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Streptococcus pyogenes Escapes Killing from Extracellular Histones through Plasminogen Binding and Activation by Streptokinase

Histones are small basic proteins and highly conserved among eukaryotes. Their main function is binding, packaging and organizing of DNA in the nucleus, but extracellular histones are also potent antimicrobial proteins. Here we found that Streptococcus pyogenes - an important human pathogen - protec...

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Detalhes bibliográficos
Publicado no:J Innate Immun
Main Authors: Nitzsche, Ramona, Köhler, Juliane, Kreikemeyer, Bernd, Oehmcke-Hecht, Sonja
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6738899/
https://ncbi.nlm.nih.gov/pubmed/27533300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000448039
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