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Streptococcus pyogenes Escapes Killing from Extracellular Histones through Plasminogen Binding and Activation by Streptokinase

Histones are small basic proteins and highly conserved among eukaryotes. Their main function is binding, packaging and organizing of DNA in the nucleus, but extracellular histones are also potent antimicrobial proteins. Here we found that Streptococcus pyogenes - an important human pathogen - protec...

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Dades bibliogràfiques
Publicat a:J Innate Immun
Autors principals: Nitzsche, Ramona, Köhler, Juliane, Kreikemeyer, Bernd, Oehmcke-Hecht, Sonja
Format: Artigo
Idioma:Inglês
Publicat: S. Karger AG 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6738899/
https://ncbi.nlm.nih.gov/pubmed/27533300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000448039
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