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Streptococcus pyogenes Escapes Killing from Extracellular Histones through Plasminogen Binding and Activation by Streptokinase

Histones are small basic proteins and highly conserved among eukaryotes. Their main function is binding, packaging and organizing of DNA in the nucleus, but extracellular histones are also potent antimicrobial proteins. Here we found that Streptococcus pyogenes - an important human pathogen - protec...

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Bibliografske podrobnosti
izdano v:J Innate Immun
Main Authors: Nitzsche, Ramona, Köhler, Juliane, Kreikemeyer, Bernd, Oehmcke-Hecht, Sonja
Format: Artigo
Jezik:Inglês
Izdano: S. Karger AG 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6738899/
https://ncbi.nlm.nih.gov/pubmed/27533300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000448039
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