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Streptococcus pyogenes Escapes Killing from Extracellular Histones through Plasminogen Binding and Activation by Streptokinase

Histones are small basic proteins and highly conserved among eukaryotes. Their main function is binding, packaging and organizing of DNA in the nucleus, but extracellular histones are also potent antimicrobial proteins. Here we found that Streptococcus pyogenes - an important human pathogen - protec...

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Bibliografiska uppgifter
I publikationen:J Innate Immun
Huvudupphovsmän: Nitzsche, Ramona, Köhler, Juliane, Kreikemeyer, Bernd, Oehmcke-Hecht, Sonja
Materialtyp: Artigo
Språk:Inglês
Publicerad: S. Karger AG 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6738899/
https://ncbi.nlm.nih.gov/pubmed/27533300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000448039
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