A Bromodomain-Containing Protein 4 (BRD4) Inhibitor Suppresses Angiogenesis by Regulating AP-1 Expression

Angiogenesis dysregulation contributes to inflammation, infections, immune disorders, and carcinogenesis. Bromodomain-containing protein 4 (BRD4) is an epigenetic reader that recognizes histone proteins and acts as a transcriptional regulator to trigger tumor growth and the inflammatory response. Th...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Zhou, Zijun, Li, Xiaoming, Liu, Zhiqing, Huang, Lixun, Yao, Yuying, Li, Liuyou, Chen, Jian, Zhang, Rongxin, Zhou, Jia, Wang, Lijing, Zhang, Qian-Qian
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7381267/
https://ncbi.nlm.nih.gov/pubmed/32765266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.01043
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