The Third Generation Anti-HER2 Chimeric Antigen Receptor Mouse T Cells Alone or Together With Anti-PD1 Antibody Inhibits the Growth of Mouse Breast Tumor Cells Expressing HER2 in vitro and in Immune Competent Mice

Chimeric Antigen Receptor (CAR)-T cells have great efficacy against CD19(+) leukemia but little success for solid tumors. This study explored the effectiveness of third generation anti-HER2 CAR-T cells alone or in combination with anti-PD1 antibody on breast tumor cells expressing HER2 in vitro and...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Li, Panyuan, Yang, Lingcong, Li, Tong, Bin, Shufang, Sun, Bohao, Huang, Yuting, Yang, Kaiyan, Shan, Daming, Gu, Haihua, Li, Hongzhi
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Oncology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7381237/
https://ncbi.nlm.nih.gov/pubmed/32766150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.01143
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