Targeting Androgen Receptor in Treating HER2 Positive Breast Cancer

Androgen receptor (AR) is widely expressed in different subtypes of breast cancer (BC). However, it is unclear how AR functions in HER2 positive (+) BC. Knockdown of AR with shRNAs and a new generation anti-androgen drug, Enzalutamide, were used to explore the involvement of AR on the growth of HER2...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: He, Licai, Du, Zhuanyun, Xiong, Xusheng, Ma, Hua, Zhu, Zhenfeng, Gao, Hongwei, Cao, Jiawei, Li, Tong, Li, Hongzhi, Yang, Kaiyan, Chen, Guorong, Richer, Jennifer K., Gu, Haihua
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5674043/
https://ncbi.nlm.nih.gov/pubmed/29109513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-14607-2
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