Overcome trastuzumab resistance of breast cancer using anti-HER2 chimeric antigen receptor T cells and PD1 blockade

Trastuzumab-resistance is still a major challenge in treating patients with HER2 positive breast cancer. In this study, we tried to overcome transtuzumab-resistance by examining the therapeutic efficacy of third generation anti-HER2 chimeric antigen receptor (CAR)-T cells alone and in combination wi...

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Detalles Bibliográficos
Publicado en:Am J Cancer Res
Autores principales: Li, Hongzhi, Yuan, Weihua, Bin, Shufang, Wu, Guang, Li, Panyuan, Liu, Min, Yang, Jifeng, Li, Xiang, Yang, Kaiyan, Gu, Haihua
Formato: Artigo
Lenguaje:Inglês
Publicado: e-Century Publishing Corporation 2020
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7061754/
https://ncbi.nlm.nih.gov/pubmed/32195036
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