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Complex Destabilization in the Mitochondrial Chaperonin Hsp60 Leads to Disease
Several neurological disorders have been linked to mutations in chaperonin genes and more specifically to the HSPD1 gene. In humans, HSPD1 encodes the mitochondrial Heat Shock Protein 60 (mtHsp60) chaperonin, which carries out essential protein folding reactions that help maintain mitochondrial and...
में बचाया:
| में प्रकाशित: | Front Mol Biosci |
|---|---|
| मुख्य लेखकों: | , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Frontiers Media S.A.
2020
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7381220/ https://ncbi.nlm.nih.gov/pubmed/32766281 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2020.00159 |
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