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Complex Destabilization in the Mitochondrial Chaperonin Hsp60 Leads to Disease
Several neurological disorders have been linked to mutations in chaperonin genes and more specifically to the HSPD1 gene. In humans, HSPD1 encodes the mitochondrial Heat Shock Protein 60 (mtHsp60) chaperonin, which carries out essential protein folding reactions that help maintain mitochondrial and...
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| Veröffentlicht in: | Front Mol Biosci |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Frontiers Media S.A.
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7381220/ https://ncbi.nlm.nih.gov/pubmed/32766281 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2020.00159 |
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