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Disease-Associated Mutations in the HSPD1 Gene Encoding the Large Subunit of the Mitochondrial HSP60/HSP10 Chaperonin Complex

Heat shock protein 60 (HSP60) forms together with heat shock protein 10 (HSP10) double-barrel chaperonin complexes that are essential for folding to the native state of proteins in the mitochondrial matrix space. Two extremely rare monogenic disorders have been described that are caused by missense...

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Bibliografische gegevens
Gepubliceerd in:Front Mol Biosci
Hoofdauteurs: Bross, Peter, Fernandez-Guerra, Paula
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2016
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5006179/
https://ncbi.nlm.nih.gov/pubmed/27630992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2016.00049
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