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Microglia Susceptibility to Free Bilirubin Is Age-Dependent

Increased concentrations of unconjugated bilirubin (UCB), namely its free fraction (Bf), in neonatal life may cause transient or definitive injury to neurons and glial cells. We demonstrated that UCB damages neurons and glial cells by compromising oligodendrocyte maturation and myelination, and by a...

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Bibliografiske detaljer
Udgivet i:Front Pharmacol
Main Authors: Vaz, Ana Rita, Falcão, Ana Sofia, Scarpa, Eleonora, Semproni, Carlotta, Brites, Dora
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7381152/
https://ncbi.nlm.nih.gov/pubmed/32765258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.01012
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