Exosomal lncRNA PCAT-1 promotes Kras-associated chemoresistance via immunosuppressive miR-182/miR-217 signaling and p27/CDK6 regulation

Immunosuppressive chemoresistance is a major burden in lung cancer. Recent data reveal that long noncoding RNAs (lncRNAs) present in the lung tumor microenvironment are implicated in chemoresistant-related immune deregulation, and metastasis but their exact pathogenic role is still unknown. In this...

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Bibliografische gegevens
Gepubliceerd in:Oncotarget
Hoofdauteurs: Domvri, Kalliopi, Petanidis, Savvas, Anestakis, Doxakis, Porpodis, Konstantinos, Bai, Chong, Zarogoulidis, Paul, Freitag, Lutz, Hohenforst-Schmidt, Wolfgang, Katopodi, Theodora
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Impact Journals LLC 2020
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Research Paper
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7381096/
https://ncbi.nlm.nih.gov/pubmed/32754302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27675
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